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Gene Synthesis for Complex Sequences

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European research labs trust BioCat for high-GC, repetitive, and difficult constructs that other providers reject.
No hidden fees added after your order is confirmed. Ever.

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Three Reasons Labs Choose BioCat:

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Sequence Guarantee

If synthesis cannot be completed, we will inform you before any charges apply. In most cases, failed synthesis incurs no fee. Any exceptions are communicated clearly in your quote before you commit.

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Free Pre-Quote Complexity Check

A PhD scientist evaluates your sequence before we quote. You get an honest feasibility assessment, not a price that changes at checkout.

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Quote Turnaround Within One Business Day

Complex sequences quoted within one business day. Transparent pricing, no surprises.

Why Complex Sequences Fail With Other Providers

Not every gene synthesis provider handles difficult sequences the same way. The common failure pattern: a sequence is accepted, queued, and then cancelled weeks later after synthesis attempts fail, or a complexity surcharge is added to your invoice that was not in the original quote.

Sequences that routinely cause problems include:

  • High GC content (above 70%), where base pairing creates synthesis-blocking secondary structures

  • Tandem repeats and low-complexity regions that create assembly and verification challenges

  • Large constructs above 5 kb where assembly complexity compounds errors

  • Unusual codon usage profiles for non-standard expression systems

BioCat assesses complex sequences before quoting, not after accepting your order.

What you are quoted is what you pay.

The BioCat Difference

We are a specialist distributor, not a high-volume synthesis factory. That distinction shapes how we handle every order.

Transparent pricing

Standard sequences start from EUR 110. Complex constructs are quoted individually after a free feasibility review. You will never receive a bill that does not match your quote.

Expert sequence review

Before we quote a complex construct, a scientist evaluates your sequence. We flag risks, suggest design improvements where relevant, and give you an honest timeline. If we cannot make it, we tell you immediately.

European ordering advantage

BioCat is based in Germany. Orders are placed and managed locally: straightforward EU invoicing, fast regional shipping, no import customs delays, and biosecurity compliance handled within EU regulatory frameworks.

Scientific partnership

We offer free codon optimization, sequence advice, and direct access to technical support. For labs that have been burned by black-box providers, working with BioCat feels different.

 

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Who We Work With

BioCat gene synthesis is used by:

Academic research labs

working on protein expression, functional genomics, and synthetic biology
Academic research labs

Biotech and pharma

research teams with active construct pipelines needing reliable throughput
Biotech and pharma

Senior researchers and lab managers

responsible for construct quality and timeline delivery
Senior researchers and lab managers

Principal Investigators

planning multi-gene projects who need volume pricing and a supplier they can trust across the year
Principal Investigators

Pricing Overview

Standard sequence pricing is fixed and transparent. Complex sequences are assessed individually after a free feasibility review.

Sequence Type    

Length    

Price
 Standard gene  Up to 500 bp Fixed: EUR 110
 Standard gene  501 - 3,000 bp EUR 0.22/bp
 Standard gene  3,001 - 5,000 bp EUR 0.29/bp
Gene fragments Up to 2,000 bp From EUR 93
Complex sequences  All lengths  Quoted individually
10+ gene projects  Any  Volume pricing available

 

Volume discounts apply to projects of 10 or more sequences. No minimum order size. No post-order fees for complexity. Contact us for a project-level quote.

 

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Frequently Asked Questions

Which gene synthesis provider is best for complex sequences?

BioCat specializes in high-GC, repetitive, and structurally difficult sequences that commodity providers routinely reject or surcharge. Every sequence is assessed by a PhD scientist before quoting, so the price you receive reflects the actual complexity of your construct. We give an honest assessment for each sequence before you commit and offer competitive and reliable prices.

How much does gene synthesis cost in Europe?

Standard sequences at BioCat start at a fixed EUR 110 for constructs under 500 bp. For 501-3,000 bp the price is EUR 0.22 per base pair; for 3,001-5,000 bp it is EUR 0.29 per base pair. Gene fragments up to 2,000 bp start from EUR 93. Complex or longer sequences are quoted individually after a free feasibility assessment. There are no hidden complexity surcharges.

What happens if my gene synthesis fails?

If synthesis cannot be completed, there is no charge. Any exceptions are communicated in your quote before the order is confirmed. We never add any additional fees without our customers' approval.

Can you synthesize high-GC content genes?

Yes. We routinely synthesize sequences with GC content up to approximately 80%, and in some cases beyond that. Highly challenging sequences may incur a higher quoted price due to increased process complexity, and this will be communicated clearly before the order is confirmed.

Do you charge extra for difficult sequences?

If a sequence requires additional synthesis steps due to complexity, the price will be higher than our standard rate. This is always communicated upfront in your quote, following a free feasibility review. There are no surcharges added after ordering.

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